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doi: 10.1038/oby.2010.150 29 PirchioRGraziadioCColaoAPivonelloRAuriemmaRS

Nobiletin , a flavone found in citrus peels, exerted anti-inflammatory effects in TNBS-induced colitis through the downregulation of iNOS and COX-2 expression, restoring barrier function through the inhibition of the Akt-NF-B-MLCK pathway [111]